El Cuerpo
Académico de Partículas Campos y Relatividad General invita
cordialmente a su próximo seminario
Validation and
application of Monte Carlo codes for treatment planning in ion beam therapy
Till Böhlen, Ph.
D.
CERN
Este
seminario se llevará a cabo en la
Sala de Conferencias (111B/302)
Miércoles 28 de marzo de 2012
12:00 hrs.
Resumen:
External radiation therapy with protons and ions, so-called hadron
therapy, is becoming more popular with an ever increasing number of treatment
facilities being operational or in construction in recent years. Protons and ions
allow to deliver highly conformal treatment fields due
to their inverse dose-depth profile (Bragg peak) which allows to target the tumour while sparing surrounding normal tissues. Heavier
ions such as carbon ions exhibit additionally enhanced radiobiological properties
in the tumour region which are advantageous, especially
for treating radio-resistant hypoxic tumours. The
talk outlines fundamental physics, biological and technical aspects of external
radiation therapy with protons and ions before focusing on examples of applications
and validations of Monte Carlo (MC) particle transport codes for hadron therapy
treatment planning. Applications of MC codes for hadron therapy include: beam modelling (beam line), generation of physical TPS input
data, support for dosimetric and biological
experiments, support for in-vivo treatment verification
(e.g. with PET), out-of-field patient dose estimations, radioprotection,
re-calculation of optimized treatment plans, and fully MC-optimized treatment
planning.